EHR Integration Patterns for Bedside Devices
HL7 v2, FHIR, SMART on FHIR, and CDS Hooks — when to use each, and why most rooms still run all four.
12 min readUpdated July 8, 20263 topics
The four integration layers
Almost every EHR integration a hospital ships in 2026 uses one of four patterns:
- HL7 v2 messages over MLLP — vitals, ADT, orders, results. High volume, low ceremony.
- FHIR REST APIs — modern read/write for third-party applications, patient-facing apps, and analytics.
- SMART on FHIR — an OAuth 2.0 profile that lets a third-party app launch inside the EHR with a scoped session.
- CDS Hooks — a webhook fired by the EHR at defined workflow points (order entry, medication review) that returns cards a clinician can act on.
Typical bedside data flows
| Data | Source | Standard | Frequency |
|---|---|---|---|
| Continuous vitals | Bedside monitor | HL7 v2 ORU^R01 via MDI gateway | 1/min |
| Waveforms | Bedside monitor | IEEE 11073-10101 nomenclature, proprietary transport | 250–500 Hz |
| Infusion status | Pump / gateway | HL7 v2 or vendor API | On change |
| Bed status | Smart bed | HL7 v2 or FHIR Observation | On change |
| Order/result review app | Third party | SMART on FHIR | On launch |
| Sepsis alert card | Analytics service | CDS Hooks (medication-prescribe) | On order |
When to use which
- If the data is event-driven and high-volume (vitals, ADT, orders): HL7 v2.
- If a third-party UI needs to read or write patient data on demand: FHIR REST.
- If the third-party UI must launch inside the chart: SMART on FHIR.
- If a clinical decision should surface at a specific workflow moment: CDS Hooks.
Standards reference
- HL7 v2.5.1 / v2.8 — event-driven messaging.
- HL7 FHIR R4 — resource-based APIs; USCDI-aligned in the US.
- SMART App Launch 2.0 — OAuth 2.0 + OpenID Connect profile.
- CDS Hooks 2.0 — webhook specification.
- 21st Century Cures Act / ONC Certification — the US regulatory driver.
References & further reading
- 1HL7 FHIR R4 Specification
- 2SMART App Launch Framework 2.0.0
- 3CDS Hooks Specification 2.0
- 4ONC 21st Century Cures Act Final Rule (45 CFR Part 170)
- 5IEEE 11073-10101 Nomenclature
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